Proteome Analysis of Leptospira interrogans Virulent Strain
نویسندگان
چکیده
منابع مشابه
Proteome Analysis of Leptospira interrogans Virulent Strain
Leptospirosis is a worldwide zoonotic infection of human and veterinary concern. Caused by pathogenic spirochetes of the genus Leptospira, the disease presents greater incidence in tropical and subtropical regions. The identification of proteins that could be involved in the bacteria host interactions may facilitate the search for immune protective antigens. We report the proteomic analysis of ...
متن کاملGlobal Proteome Analysis of Leptospira interrogans
Comparative global proteome analyses were performed on Leptospira interrogans serovar Copenhageni grown under conventional in vitro conditions and those mimicking in vivo conditions (iron limitation and serum presence). Proteomic analyses were conducted using iTRAQ and LC-ESI-tandem mass spectrometry complemented with two-dimensional gel electrophoresis and MALDI-TOF mass spectrometry. A total ...
متن کاملWhole-genome sequencing of Leptospira interrogans from southern Brazil: genetic features of a highly virulent strain
BACKGROUND Leptospirosis is the most widespread zoonotic disease. It is caused by infection with pathogenic Leptospira species, of which over 300 serovars have been described. The accurate identification of the causative Leptospira spp. is required to ascertain the pathogenic status of the local isolates. OBJECTIVES This study aimed to obtain the complete genome sequence of a virulent Leptospir...
متن کاملCharacterization of a virulent Leptospira interrogans strain isolated from an abandoned swimming pool
Pathogenic Leptospira spp. are the etiological agents of leptospirosis, an important disease of both humans and animals. In urban settings, L. interrogans serovars are the predominant cause of disease in humans. The purpose of this study was to characterize a novel Leptospira isolate recovered from an abandoned swimming pool. Molecular characterization through sequencing of the rpoB gene reveal...
متن کاملComplete Genome Sequence of Leptospira interrogans Serovar Bratislava, Strain PigK151
Leptospira interrogans serovar Bratislava infection occurs in multiple domestic and wildlife species and is associated with poor reproductive performance in swine and horses. We present the complete genome assembly of strain PigK151 comprising two chromosomes, CI (4.457 Mbp) and CII (358 kbp).
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ژورنال
عنوان ژورنال: The Open Microbiology Journal
سال: 2009
ISSN: 1874-2858
DOI: 10.2174/1874285800903010069